Milbemax dog S | 2,5 mg/25 mg | 4 tablets

Leaflet Milbemax tablets for small dogs and puppies

USES
Milbemax is abroad spectrum wormer. It is indicated in the dog for the treatment of mixed infections by immature and adult cestodes andnematodes of the following species:

• Cestodes: Dipylidium caninum, Taenia spp., Echinococcus spp., Mesocestoides spp 
• Nematodes: Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Trichuris vulpis. Crenosoma vulpis(reduction of the level of infection)

Angiostrongylus vasorum (reduction of the level of infection; see specific treatment schedule under dosage and administration).

Milbemax can also be used in the prevention of heartworm disease (Dirofilaria immitis), if concomitant treatment against cestodes is indicated. In this case the product should be administered monthly.

CONTRA-INDICATIONS
Do not use in dogs of less than 2 weeks of age and/or weighing less than 0.5 kg.

Pregnancy and lactation
Milbemax can be used in breeding dogs including pregnant and lactating bitches.

DOSAGE AND ADMINISTRATION
Milbemax is given by oral administration with or after some food.

Depending on the bodyweight of the dog, the practical dosing is as follows:

In cases where heartworm disease prevention is used and at the same time treatment against tapeworm is required, Milbemax can replace the monovalent product for the prevention of heartworm disease.

For Angiostrongylus vasorum infection, milbemycin oxime should be given four times at weekly intervals. It is recommended, where concomitant treatment against cestodes is indicated, to treat once with Milbemax and continue with the monovalent product containing milbemycin oxime alone, for the remaining three weekly treatments.

PRECAUTIONS FOR USE
Treatment of dogs with a high number of circulating microfilariae can sometimes lead to the appearance of hypersensitivity reactions, such as pale mucous membranes, vomiting, trembling, laboured breathing or excessive salivation. These reactions are associated with the release of proteins from dead or dying microfilariae and are not a direct toxic effect of the product. The use in dogs suffering from microfilaremia is thus not recommended.
In heartworm risk-areas, or in the case it is known that a dog has been travelling to and from heartworm risk regions, before using Milbemax, a veterinary consultation is advised to exclude the presence of any concurrent infestation of Dirofilaria immitis. In the case of a positive diagnosis, adulticidal therapy is indicated before administering Milbemax.
Echinococcosis represents a hazard for humans. In case of Echinococcosis, specific guidelines on the treatment and follow up and on the safeguard of  persons have to be followed. Experts or institutes of parasitology should be consulted. No studies have been performed with severely debilitated dogs or individuals with seriously compromised kidney or liver function. The product is not recommended for such animals or only according to a benefit/risk assessment by the responsible veterinarian.
In dogs less than 4 weeks old, tapeworm infection is unusual. Treatment of animals less than 4 weeks old with a combination product may therefore not be necessary.
Parasite resistance to any particular class  of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.
In case of overdosing, hydriasis, depression, drooling, paresis, trembling and/or staggered gait can occur in some dogs. The symptoms will disappear spontaneously within a day. No antidote is known
For animal treatment only. Wash hands after use.
In the event of accidental ingestion of the tablets, particularly by a child, seek medical advice and show the doctor the pack and/or the leaflet.

Storage precautions
Do not store above 30°C.
Keep blister in the outer carton to protect from light. In-use shelf life for half tablets is 1 month.
Keep out of the reach and sight of children.